SEARCH


UPCOMING LIVE SEMINARS
 






Pharmacokinetics: A Comprehensive Overview of Principles and Applications

Please check back later for this seminar's current schedule, or review our other live seminars for similar courses.

Course Description 

The course will provide participants with a comprehensive overview of pharmacokinetics by integrating concepts in physiology and mathematics. At the end of this seminar, attendees will understand fundamental pharmacokinetic concepts and be able to use them to design pharmacokinetic studies, compute pharmacokinetic parameters, and predict the effect of physiological and formulation changes on the pharmacokinetics of drugs. The instructor will provide an overview of the anatomy and physiology of organ systems relevant to drug absorption, distribution, metabolism, and excretion, explain pharmacokinetic concepts, demonstrate computation of pharmacokinetic parameters after intravenous and oral doses, and highlight concepts in bioavailability, bioequivalence, and biopharmaceutics. Understanding of theoretical principles will be facilitated by numerous practical examples from the literature, and through case studies. Periodic review and reinforcement of important concepts will be achieved through discussions, and completion of a series of in-class assignments. 

Learning Objectives 

  • Understand the anatomy and physiology of systems involved in drug absorption, distribution and elimination 
  • Compute pharmacokinetic parameters after intravenous and oral drug administration 
  • Design pharmacokinetic studies 
  • Analyze and interpret data from pharmacokinetic studies 
  • Evaluate bioequivalence data 
  • Predict the effect of physiological and formulation changes on the pharmacokinetics of drugs 
Who Should Attend

  • This course is designed for individuals working in the pharmaceutical industry with degrees in biology, chemistry, or chemical engineering who desire an understanding of the fundamental principles and concepts in pharmacokinetics 
Instructor

The course will be led by one of the following instructors: 

Anil D’Mello, Ph.D. 

Click here for complete trainer biographies 

Course Outline 

Day 1: 8:30 a.m. – 4:30 p.m. 

  • Anatomy and Physiology: Anatomy and physiology of systems responsible for drug absorption, distribution, metabolism, and excretion 
  • Intravenous Dose: Conceptual description and computation of half-life, volume of distribution, area under the plasma concentration – time curve, and clearance 
  • Oral Absorption: Description of the phases in drug absorption, computation of half-life, volume of distribution, area under the plasma  concentration – time curve, clearance, Cmax, and tmax; effect of alterations in pharmacokinetic parameters on the area under the plasma concentration – time curve, Cmax, and tmax of the drug 

Day 2: 8:30 a.m. – 4:30 p.m. 

  • Bioavailability and Bioequivalence: Definition of terms and computation of bioavailability and bioequivalence; design of bioavailability studies; historical perspective of statistical techniques used to evaluate bioequivalence data 
  • Physiological and Formulation Factors Affecting Drug Absorption: Effect of food, drug solubility, permeability, and surface area on the rate and extent of drug absorption 
  • Clearance Concepts: Physiological model for organ clearance and the effect of alterations in organ blood flow, intrinsic clearance, and plasma protein binding on drug pharmacokinetics 

Interactive Activities 

  • Classroom discussions customized to participants’ backgrounds and questions 
  • A series of in-class assignments 
  • Group examination of case studies 

 

Registration Fees

Registration fees include assorted breakfast items that will be available each day ½ hour prior to the start of the seminar. Also included is a Networking Lunch that will be served each training day. 

Special rates are available for multiple attendees from the same organization.  Contact Melissa Dolen at 781-972-5418 to discuss your options and take advantage of the savings. 

Click here for our seminar cancellation policy 

Accreditation Information

ACPE LogoBarnett International is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.  Participants will receive 15 hours (1.5 CEUs) of continuing education credit for full participation, including the completion of a pre-test, post-test and program evaluation.  Barnett International will mail ACPE statements within three weeks of program completion.  ACPE# 0778-0000-13-037-L01-P. Released: 10/13. 

Hold this course at your company! 

For more information, contact Naila Ganatra at (215) 413-2471. 

FOLLOW US ON: 

LinkedIn twitter Facebook 


On-Demand GCP Refresher Training 

Too busy to attend a course? Our newly-released GCP eLearning course may be your solution!
For details on our scenario-based practical GCP application on-demand course, click here.


GCP for Investigators
 

Barnett’s scenario-based eLearning course is designed with the busy Principal Investigator in mind.  Based on real-life scenarios encountered by investigative site teams, this highly focused 7-module GCP training is designed to ensure comprehensive understanding of the key components of GCP.

For more details on this scenario-based eGCP program for investigators please click here. 


BARNETT CATALOG The Barnett Catalogue is your comprehensive guide to the myriad live, web, and custom training opportunities offered throughout the year. 

Jan - July 2014 Edition

Winter CatalogDownload Today!  

Blended Curriculum Path for the CRA, CRC, and Project Manager

BCP Cover

Download Today! 

 

 

 


 

DVD IconWEB SEMINAR ARCHIVE 

 View Catalog of Offerings   

New Titles added every month! 
Course Alumni Save 50% 


Live SeminarLIVE SEMINARS

Monitoring Clinical Drug Studies: Intermediate 

Informed Consent Content & Process Requirements for Biobanking Studies 

Auditing Techniques for Clinical Research Professionals 


Web SeminarWEB SEMINARS

10-Week CRA & CRC Beginner Program  

Trial Master File (TMF) for Sponsors: Set-Up and Maintenance 

Use of Notes to File in Clinical Trial Essential Documentation 

10-Week Clinical Research Associate (CRA) On-Boarding Program  


PublicationsPUBLICATIONS

2012 GCP Question & Answer Guide Print Edition 

2012 Good Clinical Practice Question & Answer Guide Electronic Edition 

CFR/ICH GCP Reference Guide 2012 (Spiral Bound) 

CFR/ICH GCP Reference Guide 2012 (Perfect Bound) 

PAREXEL's Bio/Pharma R&D Statistical Sourcebook 2012/2013 (Hard Copy)